Scientific Program

Conference Series Ltd invites all the participants across the globe to attend International Congress on Nosocomial and Healthcare Associated Infections Las Vegas,Nevada,USA.

Day 1 :

Keynote Forum

R Scott Hatfield

CEO & President of Infection Prevention Products Inc

Keynote: Plastic bags cause infections in healthcare

Time : 10:20-11:05

Conference Series NHAI 2017 International Conference Keynote Speaker R Scott Hatfield photo
Biography:

R Scott Hatfield has over 25 years of experience as an Entrepreneur, has raised over 10 million in venture capital and started multiple ventures. He has designed
numerous software applications and has been a frequent speaker at various industry conferences. In 2012, he Co-Founded Infection Prevention Products Inc. He
has studied and continues to study and participate in numerous educational programs in healthcare and infection prevention. He has done exhaustive research on
the dangers of plastic bags in healthcare and worked closely with the biology professor at CSUC testing the microbial adherence on a nasal cannula stored in a
plastic bag. He received a certificate as an Infection Preventionist and has spoken at a number of infection prevention education seminars. His business promotes
the use of the IP-Pouch® and IP-Pouch® family of products as an alternative to plastic bags.

Abstract:

The practice of storing a patient’s reusable respiratory device in plastic bags in both SNF and Hospitals cause infections.
Plastic bags cause Nosocomial Infections or HAI. Polyethylene plastic is the worst material found in a healthcare setting
for bacterial adherence and growth according to the Journal of Clinical Microbiology. The practice of storing a patient’s reusable
respiratory device in a plastic bag causes infections not only on the patient, but the bacteria from the patient can be easily
spread throughout a facility when plastic bags are replaced or simply touched. According to a study from PubMed, the
adherence of bacteria was the highest on polyethylene catheters. Bacterial adherence was 1,700% greater on polyethylene
vs. steel catheters. Studies done at CSUC documented the microbial adherence on a nasal cannula placed in a plastic bag vs. a
breathable polypropylene mesh bag. The recoverable bacteria decreased 84-99% in just one hour in the mesh bag compared
to that of the plastic bag. The respiratory region is the most vulnerable area on our body for contracting infections. 95% of
healthy human adults were infected with the cold virus when just 1-30 particles of the cold virus were place in their nostrils.
Infection Prevention Products Inc., will explain why plastic bags should not be used to store a patient’s reusable respiratory
device. Infection Prevention Products Inc., show studies where using a breathable moisture wicking pouch drastically reduces
infections in healthcare facilities compared to the use of plastic bags.

Break: Networking & Refreshment Break 11:05-11:20

Keynote Forum

Jorg Imberger

University of Miami, USA

Keynote: Consequences of connecting human tribal behaviour to the internet

Time : 11:20-12:05

Conference Series NHAI 2017 International Conference Keynote Speaker Jorg Imberger photo
Biography:

Jörg Imberger received his PhD from UCB and became Australia’s Youngest Full Professor at 35. His research interest are in environmental engineering as applied
to rivers, lakes, estuaries and coastal seas. Recent foci include strategies for sustaining functionality of aquatic systems in a changing world. He is a Fellow of 10
international academies and the recipient of 30 major honours including the Onassis International Prize, the Stockholm Water Prize and Member of the order of
Australia. He has published five books, with two in preparation, contributed to 19 books and has published 251 journals papers. Google Scholar credits him with
18,530 citations and an h-Index of 62.

Abstract:

Human organizational tribal social structures have developed over 150,000 years of human evolution. The results is a
nested hierarchical set of sub-organizational groupings, consisting of family groups at the base, social, religious and
activity groupings all functioning within an overlaid governance structure with an elder acting as a leader overseeing the
behavior of all the subgroups. The tribal structure provides a reference point for individual norms, as a ladder to advance and
learn new skills and most importantly, it provided the organizational response structure against real and or perceived external
threats. Advances in communication technologies provided the impitus organizational adaption; first individual to individual
communications via intuition, then gestures, languages, writing, mail, telephone, telex, emails then it became non specific via
websites and social media. Communication is now global via the cloud. This has cut the two way communication within the
human tribal structures which we hypothesise may account for our society’s woes with depression and narcissism. Block-chain
technology is returning individual’s identities, by removed the need for intermediaries and permanent connections online.
The identity, however, is in a global context. In this talk I explore the consequences of breaking the traditional connections
that humans had developed through using our eyes, smell, hearing and touch and replacing these connections with a global
connectivity. Taking the past response of indigenous people when overrun by invaders, the business as usual scenario, will
likely bring a huge increase in mental illness. To insure against this possibility it is essential that humans adjust their tribal way
of operating. The tools to cycle back to tribal connections in a global space are at hand and only involve some straight forward
engineering infrastructure adjustments, changes in our education curricula and a willingness to accept that the world is now
finite.

Keynote Forum

Stephen Hsu

Augusta University, USA

Keynote: What does green tea have to do with fighting germs?

Time : 12:05-12:50

Conference Series NHAI 2017 International Conference Keynote Speaker Stephen Hsu photo
Biography:

Stephen Hsu earned his Bachelor’s degree from Wuhan University in China, and Master of Arts degree from Montclair State University and PhD degree from the
University of Cincinnati. He spent four years at Memorial Sloan-Kettering Cancer Center before joining the Medical College of Georgia (now part of Augusta University).
He is well-recognized in translational research and inventions on the benefits of green tea polyphenols, with more than 60 publications. His research is supported
by grants from NIH, US Army and other funding agencies. He has been invited to speak at various CE courses, and domestic and international conferences.

Abstract:

Tea is the second most popular beverage in the world next to water. Benefits of tea polyphenols, especially the polyphenols
from unfermented green tea leaves, have been studies extensively. While the antioxidant, anticancer, and anti-inflammatory
activities of green tea extracts have been well-documented, the antimicrobial activities of green tea and its extracts were only
scientifically investigated in recent years. Many groups around the globe reported promising results regarding the antibacterial
and antiviral properties of green tea polyphenols, especially epigallocatechin-3-gallate (EGCG), the most abundant polyphenol
from green tea. However, due to the water-soluble and chemically unstable nature of these antioxidant compounds, green
tea polyphenols in their original forms are difficult to incorporate into practical products for antimicrobial use, such as
topical formulations, disinfectants, and sanitizers. To overcome these obstacles, we have focused on certain modified green
tea polyphenols that have lipid-solubility and stable activity against microbes that are resistent to conventional disinfectant
methods. We discovered that the lipid-soluble tea polyphenols (LTP) possess potent virucidal activities against many viruses,
including alcohol-resistant nonenveloped viruses such as poliovirus and norovirus. Both In vitro and clinical studies have
demonstrated that LTP, in the form of EGCG-esters, are effective against herpes simplex viruses and related symptoms such
as herpes labialis, without adverse effect. These findings lead to recently created topical applications for treating herpes labialis
and alcohol-based hand sanitizer formulations containing LTP. We are currently investigating the sporicidal mechanism of
LTP to develop strategies of using these nontoxic compounds to better protect populations from microbial infections.

  • Device-Related Infections | Microbial Biofilms | Antibiotics and Antimicrobial Use
Speaker

Chair

Hua-Wei Chen

Naval Medical Research Center, USA

Speaker

Co-Chair

Sami Rtimi

Swiss Federal Institute of Technology, Switzerland

Speaker
Biography:

Hua-Wei Chen has received his PhD from the University of Maryland at College Park and completed his Post-doctoral studies from National Cancer Institute. He
is a Member of the American Society for Rickettsiology. He has been working in the Viral and Rickettsial Diseases Department since 2004 on Rickettsioses, and
other closely related diseases. He has published more than 25 papers in reputed scientific journals.

Abstract:

Coxiella burnetii, the bacterium causing Q fever, is an obligate intracellular biosafety level 3 agent. PCR based diagnostic assays have
been developed for detecting C. burnetii DNA in cell cultures and clinical samples. Because PCR method requires specialized
equipment and extensive end user training, it is not suitable for routine work especially in the resource-constrained areas. We have
developed a loop-mediated isothermal amplification (LAMP) assay with lyophilized reagents to detect the presence of C. burnetii
in patient samples. This method can be performed at a single temperature around 60°C with a heating block. The sensitivity of this
LAMP assay is very similar to PCR method with a detection limit at about 25 copies. The amplified DNA products were visualized
with a naked eyes using hydroxynaphthol blue or addition of SYBR green dye in the reaction with a UV lamp. The stability of the
lyophilized reagents were tested and followed for 24 months, 18 months, and 42 days when the reagents were stored at 4°C, 25°C, and
37°C, respectively. The results showed the lyophlized reagents retain the same reactivity as freshly prepared reagents when stored at
4°C for 24 months, 25°C for 28 days, and 2 days at 37°C. The lyophilized LAMP reagents are perfect to be used in resource-limited
settings where Q fever is endemic

Sami Rtimi

Ecole Polytechnique Fédérale de Lausanne, Switzerland

Title: Antibacterial surfaces with presenting redox properties for indoor hospital surfaces
Speaker
Biography:

Sami Rtimi is a Scientist presently working at Swiss Federal Institute of Technology.

Abstract:

Surfaces coating is drawing attention as effective method to kill bacteria by contact in hospital facilities. Many coating methods
were studied and showed antibacterial capability. Many of them have the drawback of leaching out heavy metals, metal oxides,
antibiotics/antiseptics leading to the degradation of the environment and the ecosystem. Physical vapor deposition was used to
prepare metal oxides uniform, adhesive and ultra-thin coatings. In this direction, we provide insight into two different uniform
atomic-scale microstructures of Cu and Ti-oxides sputtered on polyethylene-based serum bags leading to fast bacterial inactivation
without losing the visibility of the liquid inside the bag. Co-sputtered (CuOx-TiO2-PE) consists mainly of CuO led to bacterial
inactivation kinetics within 20 min under very low intensity actinic/indoor light. This light is similar to the ones used in hospital
facilities and public places in Europe. The sequential sputtered (CuOx/TiO2-PE) consist mainly of Cu2O led to bacterial inactivation
within 90 minutes. By X-ray photoelectron microscopy (XPS), redox catalysis was observed to proceed during bacterial inactivation
for both coatings. The energetics and mechanism for the bacterial inactivation of E. coli on the co-sputtered and the sequential
sputtered catalysts are suggested. The Cu and Ti uniform distribution on the catalyst surface was mapped along the coating thickness
by wavelength dispersive spectrometry (WDS). By fluorescence stereomicroscopy the inactivation time of E. coli was found to be
in agreement with the times found by agar plating. The short-lived transients on the co-sputtered catalyst surface were followed by
femtosecond spectroscopy in the fs-ps region. By atomic force microscopy (AFM) the roughness of the co-sputtered (CuO) and
sequentially sputtered samples (Cu2O) were found respectively to present values 1.63 nm and 22.92 nm and the magnitude of the
roughness was correlated with the bacterial inactivation times. A deep understanding of the quantitative parameters controlling both
coatings leading to bacterial inactivation will be discussed.

Speaker
Biography:

Dhruv Kamlesh Mamtora has completed his MBBS in 2010 from Lokmanya Tilak Municipal Medical College, Mumbai. He also did MD in Medical Microbiology from
Government Medical College, Miraj, Maharashtra in year 2013. He is Head of Microbiology and Infection control at S L Raheja Hospital, a 150 bedded multispecialty
hospital and center of excellence for diabetes and oncology. He has published papers in journals and has been serving as Editor for pubmed indexed journal. He
is also media subject expert on infection control, microbiology, antimicrobials and outbreaks.

Abstract:

Device associated infections and morbidity associated with hospital acquired infections have tremendous impact on patient
outcomes including prolonged stay, use of higher antibiotic therapy, use of invasive devices and overall financial loss and loss of
productivity. Hospital is a 150 bedded superspeicality tertiary care center hospital with center of excellence for diabetes and oncology
in the city of mumbai. The infection control department carries out surveillance of all infections including hospital acquired infections.
The infections for which routine surveillance is done are Ventilatory associated pneumonia (VAP) and Ventilatory associated events
(VAE), Catheter associated blood stream infections (CLABSI), Catheter associated urinary tract infections (CAUTI) and Surgical
site infections(SSI). The standard definitions are followed as per NHSN definitions and as per NABH accreditation guidelines.
Culture related microbiology surveillance is done for all central lines, urine, respiratory samples (ET secretions, Mini BAL, BAL) and
surveillance sysem to track SSIs. Prevention aspect of HAIs is taken cared by bundled care approach and round the clock audits done
by 10 infection control assistants and Infection control nurses which are 2 in number. The audits include insertion audits for central
line catheters and urinary catheters which is something unique and acheived with 100% compliance for all patients. The training
is extensive and include induction and on going trainings. One to one training is given to ICU nurses by infection control nurses
and infection control officer. Rounds are taken on daily basis by infection control team and all adverse events related to infection
control are documented and root cause analysis for all events are done during validation meeting conducted by management and key
stakeholders on monthly basis. The HAIs are also one of common agenda for Hospital infection control comittee. Key success factor
include low incidence of hospital acquired infections in spite of being primarily diabetic and oncology hospital. The reason being
round the clock surveillance activity, bundled care approach compliance, continuous and on going trainings and good hand hygiene
compliance.